This book collects texts from three specialists in ancient philosophy which deal with the question of perceptive and intellective knowledge in antiquity. They try to present, in their different analyzes, the complex interrelationship among perception and thought in ancient authors, like Heraclitus, Parmenides, Democritus, Plato and Aristotle. The purpose of the texts is to expose the visible field - the perceptual knowledge domain - interacts with the invisible - the domain of reason and thought. In other words, that among them (...) there is no a radical separation of these two areas, although they are clearly distinct. (shrink)

« La mesure est le plus grand des biens » et « rien de trop » apparaissent dans les sentences attribuées aux Sept Sages de l’Antiquité Grecque. Elles font état d’une sagesse qui blâme l’excès et invite à la modération. Les échos de ces propos résonnent dans différentes périodes de l’Antiquité et chez des auteurs appartenant aux traditions les plus variées, parmi lesquels se trouve notamment Démocrite. Nombreux sont en effet les fragments qui attestent de sa condamnation des excès, de (...) sa réflexion critique sur les richesses et de son éloge de la modération et de l’équilibre entendus comme conditions du bien-être et de l’action bonne. « La juste proportion est belle en toutes choses » (DK 68 B 102), proclame le philosophe. Cette juste proportion est érigée en condition pour atteindre la « bonne humeur » ( euthymiê ) et le « bien-être » ( euestô ). La réflexion de Démocrite se fonde sur une sorte de principe économique qui s’exprime par la notion de « mesure » ( metriotês ). La capacité à être modéré est aussi le signe distinctif de l’être humain bien accompli (DK 68 B 70), et s’oppose aux différentes formes de l’avidité. Lorsque l’on examine les fragments qui traitent de ce sujet, l’on constate que le philosophe a dressé un inventaire qui prend en compte les domaines les plus divers de la vie. Il est en effet question de la mesure aussi bien dans le cadre des affections comme le plaisir et le désir, que dans celui de la satisfaction de nos besoins élémentaires. Il en est également question pour ce qui est de notre attitude à l’égard des biens matériels et des richesses. Dans cet article nous avons choisi de faire porter l’attention sur la réflexion du philosophe sur les richesses et les biens matériels, en prenant tout particulièrement en compte sa mise en cause du désir dans l’économie de la vie humaine. Classification JEL : B1. (shrink)

We present a general derivation of the Duffin-Kemmer-Petiau (D.K.P) equation on the relativistic phase space proposed by Bohm and Hiley. We consider geometric algebras and the idea of algebraic spinors due to Riesz and Cartan. The generators βμ (p) of the D.K.P algebras are constructed in the standard fashion used to construct Clifford algebras out of bilinear forms. Free D.K.P particles and D.K.P particles in a prescribed external electromagnetic field are analized and general Liouville type equations for these cases are (...) obtained. Choosing particular values for the label p we classify the different types of the D.K.P Liouville operators. (shrink)

The thought of the ancient atomists about the activity of the soul in the body is an important chapter in the history of reflection on the soul in ancient philosophy. A review of testimonies and fragments attributed to Democritus of Abdera shows its singular conception of the soul as a complex network of transactions through which it exercises, inside compound bodies, its role in driving principle of beings animated. These texts show the tension and dynamism that characterize the activity of (...) the soul and especially the close relationship between the activities of perceiving and thinking, essential activities to the economy of living beings, now for what is the management of biological life, now in terms of knowledge and human action. What we propose here is to examine how Democritus conceived the activity of the soul in its complexity and the various operations through which it accomplishes its function in the animation and the maintenance of life of animate beings, and particularly of human life. To do this, we will take as a basis the testimonies referred to the nature of the soul – especially the testimony of Aristotle and his disciples and commentators – and then examine the activities through which proceeds its role of motor principle, namely the sensations and the intellection. And, finally, we intend to demonstrate that these operations should not be considered, in the context of atomist thought, as two independent and opposed faculties or activities, but as two different levels or degree, contiguous and complementary, of one and the same activity. (shrink)

The thought of the ancient atomists about the activity of the soul in the body is an important chapter in the history of reflection on the soul in ancient philosophy. A review of testimonies and fragments attributed to Democritus of Abdera shows its singular conception of the soul as a complex network of transactions through which it exercises, inside compound bodies, its role in driving principle of beings animated. These texts show the tension and dynamism that characterize the activity of (...) the soul and especially the close relationship between the activities of perceiving and thinking, essential activities to the economy of living beings, now for what is the management of biological life, now in terms of knowledge and human action. What we propose here is to examine how Democritus conceived the activity of the soul in its complexity and the various operations through which it accomplishes its function in the animation and the maintenance of life of animate beings, and particularly of human life. To do this, we will take as a basis the testimonies referred to the nature of the soul – especially the testimony of Aristotle and his disciples and commentators – and then examine the activities through which proceeds its role of motor principle, namely the sensations and the intellection. And, finally, we intend to demonstrate that these operations should not be considered, in the context of atomist thought, as two independent and opposed faculties or activities, but as two different levels or degree, contiguous and complementary, of one and the same activity. (shrink)

"Neuroscience and Philosophy" begins with an excerpt from "Philosophical Foundations of Neuroscience," in which Maxwell Bennett and Peter Hacker question the ...

The importance of communities in strengthening the ethics of international collaborative research is increasingly highlighted, but there has been much debate about the meaning of the term ‘community’ and its specific normative contribution. We argue that ‘community’ is a contingent concept that plays an important normative role in research through the existence of morally significant interplay between notions of community and individuality. We draw on experience of community engagement in rural Kenya to illustrate two aspects of this interplay: (i) that (...) taking individual informed consent seriously involves understanding and addressing the influence of communities in which individuals’ lives are embedded; (ii) that individual participation can generate risks and benefits for communities as part of the wider implications of research. We further argue that the contingent nature of a community means that defining boundaries is generally a normative process itself, with ethical implications. Community engagement supports the enactment of normative roles; building mutual understanding and trust between researchers and community members have been important goals in Kilifi, requiring a broad range of approaches. Ethical dilemmas are continuously generated as part of these engagement activities, including the risks of perverse outcomes related to existing social relations in communities and conditions of ‘half knowing’ intrinsic to processes of developing new understandings. (shrink)

Recordings of neuronal activity in the monkey superior colliculus (SC) suggest that the two apparently independent effects of a visual distractor on both temporal (latency) and spatial (metrics) saccade parameters may be the result of lateral interactions between subpopulations of saccade-related neurons located at different sites on the motor map of the superior colliculus. One subpopulation is activated during the planing and initiation of a saccade; the other is activated by the appearance of a distractor. The inhibitory or facilitative nature (...) of this interaction depends on the distance between the distractor and the target and is consistent with the complex pattern of intrinsic and commissural collicular connections. (shrink)

Increasing ethical attention and debate is focusing on whether individuals who take part in clinical trials should be given access to post-trial care. However, the main focus of this debate has been upon drug trials undertaken in low-income settings. To broaden this debate, we report findings from interviews with individuals (n = 24) who participated in a clinical trial of a closed-loop system, which is a medical device under development for people with type 1 diabetes that automatically adjusts blood glucose (...) to help keep it within clinically recommended ranges. Individuals were recruited from UK sites and interviewed following trial close-out, at which point the closed-loop had been withdrawn. While individuals were stoical and accepting of the requirement to return the closed-loop, they also conveyed varying degrees of distress. Many described having relaxed diabetes management practices while using the closed-loop and having become deskilled as a consequence, which made reverting back to pre-trial regimens challenging. Participants also described unanticipated consequences arising from using a closed-loop. As well as deskilling, these included experiencing psychological and emotional benefits that could not be sustained after the closed-loop had been withdrawn and participants reevaluating their pre- and post-trial life in light of having used a closed-loop and now perceiving this life much more negatively. Participants also voiced frustrations about experiencing better blood glucose control using a closed-loop and then having to revert to using what they now saw as antiquated and imprecise self-management tools. We use these findings to argue that ethical debates about post-trial provisioning need to be broadened to consider potential psychological and emotional harms, and not just clinical harms, that may result from withdrawal of investigated treatments. We also suggest that individuals may benefit from information about potential nonclinical harms to help make informed decisions about trial participation. (shrink)

lecting statistics about missing bindings and macros, and other errors. This guides debugging and development efforts, leading to iterative improvements in both the tools and the quality of the converted corpus. The build system thus serves as both a production conversion engine and software test harness. We have now processed the complete arχiv collection through 2006 consisting of more than 400,000 documents (a complete run is a processor-yearsize undertaking), continuously improving our success rate. We are now able to convert more (...) than 90% of these documents to XHTML+MathML. We consider over 60% to be successes, converted with no or minor warnings. While the remaining 30% can also be converted, their quality is doubtful, due to unsupported macros or conversion errors. (shrink)

The history of the dyestuffs industry during the period 1775–1860 is interesting for three reasons. In the first place it was in connection with the manufacture of synthetic dyestuffs, begun in 1856, that the industrial research laboratory and the organization scientist first unmistakably appeared in the last decades of the nineteenth century. Secondly, there are the enigmas of W. H. Perkin, the man who discovered and manufactured the first coal-tar colours, but who retired somewhat abruptly from the industry in 1874: (...) just after the synthesis of alizarine. Thirdly, the dyestuffs industry was in intimate association with the textile industries which had for a long time been subject to frequent radical scientific and technological innovation. Among the most important of these we may mention John Smeaton's classic paper of 1759 on the maximum work obtainable from a given fall of water: a problem important not only for the abstract science of mechanics, but also for the design of waterwheels—the main source of power for the early textile mills. (The waterwheel was not, during the eighteenth century, the epitome of the quaint and picturesque: it was in the van of scientific and technical progress.) Again, the textile industries were quick to employ the Watt rotative engine; previously a two cylinder Newcomen engine had been tried out. Bleaching powders, based on Scheele's discovery of chlorine and its properties, were rapidly adopted: in this context one cannot help contrasting the indifference of medical science to Davy's early suggestion of using nitrous oxide as an anaesthetic; or Faraday's comment in 1818 on the anaesthetic power of sulphuric ether. The textile industries saw, over this period, a rapid succession of new machines, the pace of invention being so hot that in 1832 Charles Babbage reported that machines became obsolete long before they wore out. A Salford cotton mill was the first industrial establishment to use gas lighting: James Thomson, calico printer, introduced gas lighting to the town of Clitheroe when he installed it in his works. And there were many other important technical and scientific innovations. It was to supply these industries, so well accustomed to change, that the synthetic coal-tar dyestuffs were introduced from 1856 onwards. It is interesting that, so far as we can see, the appearance of these synthetic dyestuffs was the last in the series of major innovations in the textiles and related industries: at least until recent times. (shrink)

We define a new topology on the space of strong types of a given theory and use it to state an omitting types theorem for countably saturated models of the theory. As an application we show that if T is a small, stable theory of finite weight such that every elementary extension of the countably saturated model is ω-saturated then every weakly saturated model is ω-saturated.

Among bioethicists and members of the public, genetics is often regarded as unique in its ethical challenges. As medical researchers and clinicians increasingly combine genetic information with a range of non-genetic information in the study and clinical management of patients with common diseases, the unique ethical challenges attributed to genetics must be re-examined. A process of genetic routinisation that will have implications for research and clinical ethics, as well as for public conceptions of genetic information, is constituted by the emergence (...) of new forms of genetic medicine, in which genetic information is interpreted in a multifactorial frame of reference. Although the integration of genetics in medical research and treatment may be a helpful corrective to the mistaken assumptions of genetic essentialism or determinism, the routinisation of genetics may have unintended consequences for the protection of genetic information, perceptions of non-genetic information and the loss of genetic research as a laboratory for exploring issues in research and clinical ethics. Consequently, new ethical challenges are presented by the increasing routinisation of genetic information in both biomedical and public spheres. (shrink)